Topics in this Issue: July, 2003

• List of World Problems that Probiotics can help to Resolve
• What is EnzoLac?
• EnzoLac is a Probiotic and also a Prebiotic
• How does EnzoLac Work?
• Benefits of EnzoLac
• Special Features of EnzoLac
• Probiotics Reduce Veterinarian Costs
• Why are Probiotics Important Today?
• Applications
• Conclusion
• Useful Probiotic Links

Agricultural Environmental World Problems: (and Solutions where Probiotics can help in Part or in Whole)

Environmental problems concerning Ecoli in our water supply....

Deadly Viruses such as SARS, BSE Mad Cows....

Pathogenic Bacteria such as Salmonella....

Elimination of the overuse/misuse of Antibiotics....

Human conditions on the rise: Allergies, Obesity, Colon Cancer, Heart Disease, Dementia, Etc....

The problem of Desertification: Lifeless Soil....

Warming Effect (Green House Effect)....

The only fully Organically Registered Probiotic for Livestock in America.
Produced by Bio-ag Consultants & Distributors Inc.

EnzoLac is a probiotic livestock feed supplement. (also there are probiotics for human consumption)
EnzoLac is a microbial growth stimulant manufactured by using a special patented fermentation process, which produces this lactic acid, lactobacillus fermentation probiotic. Specific live plant enzymes (Kreb Cycle) are then added on a GMO free (genetically modified organisms) wheat carrier to enhance the efficiency of the probiotic and to create a balance in the digestive system to ensure optimum health and productivity.

EnzoLac is a Probiotic and also a Prebiotic
A prebiotic substance has been defined as a non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth
and/or activity of one or a limited number of bacteria in the colon. Therefore, compared to probiotics, which introduce exogenous bacteria into the
colonic microflora, a prebiotic aims at stimulating the growth of one or a limited number of the potentially health-promoting indigenous
micro-organisms, thus modulating the composition of the natural ecosystem. In recent years, increasing attention has been focussed on the possible
beneficial effects of prebiotics, such as enhanced resistance to invading pathogens, improved bowel function, anti-colon cancer properties, lipid
lowering action, improved calcium bioavailability, amongst others.

EnzoLac is a Balance of a Probiotic, a Prebiotic and also contains Specific Live Plant Enzymes:
This is an over simplification but basically this is how it works.
Enzymes are properties of all living cells that change things into usable forms. Enzymes also perform other tasks in the body as well, assisting in all bodily functions. Enzymes when eaten are put to sleep via hydrochloric acid produced by the stomach and only come back to life once further along in the digestive tract. In the digestive tract, eg. mouth, stomach, pancreas, liver and intestines, various enzymes are produced that break food down into usable form. The more enzymes that are used for digestion, the less available for all other functions. Too much of the "enzyme account" used to digest depletes the amount for basic life functions, or foods pass through without complete digestion. The undigested foods build in the intestine and leak into the blood stream. This will cause inflammation, sickness and disease will occur.
An Enzyme is one of a large class of complex protein substances of high molecular weight. Two or more atoms = 1 molecule, 1000 or more molecules = 1 macromolecule. Enzymes range from 18,000 to 60,000 atoms per molecule.
Many medical people and researchers say that since enzymes are macro molecules, we cannot absorb them., but this science can not be totally correct because bile and pancreatic enzymes are obviously absorbed, eg. nursing babies absorb antibodies from mother's milk (gamma globules).
The body has two distinct immune systems the Specific defense system and the Non-Specific defense system. This all starts in the bone marrow as T Cells with instructions from the Thymus and B Cells from the Bursa or Bowel which produces specific antibodies and goes to circulatory and lymphatic systems to search for enemies. The bloodstream has macrophages or large white blood cells that capture and carry away toxic wastes, eg. early cancer cells, excess hydrogenated fats, etc. The defense system is composed of proteins, co-enzymes, plasma protein, and glycoprotein. EnzoLac is a balance of the probiotic, the prebiotic and specific live plant enzymes. (Kreb Cycle)

Probiotics have been described as the opposite of antibiotics. While antibiotics destroy life, probiotics build up or promote life. The function of a probiotic is to improve the growth and development of the normal, desirable microbial population in the gut, allowing them to maintain domination over the undesirable organisms(a strong immune system). A probiotic can be a live (viable) culture of microbial species, a dead (nonviable) product of microbial fermentation or an extract of plant origin.

The word probiotic is derived from the Greek meaning "for life". Probiotics are "mono- or mixed cultures of live microorganisms which, when applied to animal or man, beneficially affect the host by improving the properties of the indigenous microflora". The common terms for probiotics are "friendly", "beneficial" or "healthy" bacteria. Probiotic bacteria are generally, though not exclusively, lactic acid bacteria and include Lactobacillus acidophilus, bifidobacterium, L. casei, L. bulgaricus, L. plantarum , L. casei, L. salivarius, L. rhamnosus, L. reuteri, bifidum, B. longum, B. infantis and S. thermophilus.

How does EnzoLac Work?
The normal bacteria in the gastrointestinal tract are well known for helping livestock maintain a healthy, growing condition. It is important that these bacteria be established early in life and be well maintained. If the digestive bacteria are not well maintained, the risk of infection and disease is greatly increased. Once the diseased organism is established, the animal health condition is reduced and sickness or death can occur.
Probiotics need to be ingested regularly for any health promoting properties to persist. It is possible to manipulate the composition of the gut microflora in animals through dietary supplementation with probiotics. This concept is gaining popularity throughout the world.
Probiotic effects may be due to direct action, modulation of local immunity, modifications of gut ecology or a combination of these effects.
Probiotic bacteria produce a variety of substances that are inhibitory to both gram-positive and gram-negative bacteria. These include organic acids, hydrogen peroxide and bacteriocins. These compounds may reduce not only the number of viable pathogenic organisms but may also affect bacterial metabolism and toxin production.
Competitive Exclusion - Competition for nutrients. Probiotics utilize nutrients otherwise consumed by pathogenic microorganisms. This is important because many debilitating and degenerative diseases begin in the intestinal tract.

Benefits of EnzoLac:

• strengthens helpful microbial populations and suppresses harmful bacterial growth in the digestive system
• counteracts ill effects of antibiotic treatment by sustaining the populations of good bacteria
• strengthens the immune system
• improves utilization of protein
• production of inhibitory substances.
• develops a healthier spleen
• improves overall health and productivity in all livestock
• increases conversion rates (less feed per lb. of gain)
• assists in treatment of feed/sick animals e.g. pneumonia, diarrhea, shipping fever
• gets new livestock on feed quickly
• reduces scour incidence in swine
• increases egg size in poultry
• keeps cows eating and butter fat up in hot weather
• assisting in cholesterol management
• producing B vitamins
• maximizes production
• produces quality products

• stable with an extensive shelf life, no need for refrigeration
• can be sprayed onto pelleted feeds
• can be incorporated into the grain ration, TMR (total mixed rations) or top-dressed

Increased nutritional value (better digestibility, increased absorption of vitamins and minerals)

Promotion of intestinal lactose digestion.

Positive influence on intestinal and urogenital flora (antibiotics and radiation induced colitis, yeast infections).

Prevention and reduction of intestinal tract infections (bacteria or virus induced, Candida enteritis, Helicobacter).

Regulation of gut motility (constipation, irritable bowel syndrome).

Decreased incidence and duration of diarrhea (antibiotic associated).

Maintenance of mucosal integrity.

Improvement of immune system.

Reduction of catabolic products eliminated by kidney and liver.

Better development (growth).

Anti carcinogenic, anti-mutagenic and anti-allergic activities.

Feeling of well-being.

Two areas in which the intestinal inoculant effect of probiotics is strongly documented are in suppressing neonatal scours and improving the growth of young or stressed animals. According to the growing database of research, such observations are similar across animal species.

• As long as active bacteria are administered through feed or water, there is no question that the microbial population can be shifted away from toxin-forming E. coli and other diseases, toward beneficial lactic acid producers.

Stress:
Everyday stress can affect the microbial population, and to maintain maximum digestive efficiency you need to keep the bug population on as an even keel as possible. So by regularly adding small additional populations to the existing population, you fill in the gaps left by small daily upsets, moldy feeds and avoid major shifts in the population that can decrease efficiency and cause associated problems.

In times of stress, there is a general consensus the stress causes not only immuno suppression but also causes possible interference with the establishment of protective microflora. Physiological stress such as high-low temperatures, feed deprivation, moving, handling, vaccinations; all can attribute to a gut imbalance. To reduce the risk of opportunistic pathogen load, one should consider the application of EnzoLac post stress.

Deadly Diseases: Ecoli, Sars, Mad Cows BSE, Salmonella
With the proper use of Probiotics we would have much less Ecoli in our manure and in turn, our water supply. We would eliminate the problem at the source without the expense of more chemicals in our animals, or on our land and in our water supply. Cattle fed with hay produce less than 1% the E.coli found in the feces of those fed with grain.
Not one Organic livestock farm in England got BSE Mad Cows Disease in the out break of the nineties.
The Soil Association has undertaken a thorough survey of BSE on organic farms. This revealed that there has been no recorded case of BSE in any herd which has been managed fully organically since before 1985. The use of blood and bonemeal in livestock feed is prohibited under Soil Association standards.

Pathogens:
The challenge faced in the agricultural community is the prevention of contamination of farm products with food borne pathogens, such as Salmonella and campylobacter spp. In relation to, for example, Salmonella, much is known about the sources of infection, the means of transmission, and the management factors necessary for effective control. In chicken flocks, for example, infection can arise from vertical transmission from infected breeders, horizontal transmission from contaminated feed or replacements. Infection can also come from a variety of environmental sources such as wild birds, rodents, insects and other factors that can support the viability of the bacteria. Farm managers have instituted strict bio-security programs to reduce the risks associated with salmonella and other pathogens. Programs such as sanitation and disinfections, vaccinations and other programs have been instituted to minimize pathogens, yet their re-occurrence continues to haunt farm managers. Towards this challenge, Bio-Ag Consultants & Distributors have developed products incorporating a Probiotic, that can assist farm managers in their control programs.

Disease affects the animal's performance by depressing the rate of growth, either through low-grade toxicity or impaired physiologic or metabolic activities. How much the performance is depressed by sub clinical or chronic disease is variable. Animal performance in response to feeding probiotics is influenced by the inoculant level fed, the animal species tested, and the animal's stage of maturity, plane of production, level of stress, and rearing environment. The speed with which the gut becomes inoculated with a given bacteria depends on environmental contamination and probiotic administration.
Health is probably the most important attribute because almost all disease inevitably results in a degree of metabolic inefficiency.
A strong immune system in livestock and humans has proven to ward off disease.

Antibiotics and probiotics
Through the enormous use and misuse of antibiotics within the livestock industry we have become increasingly more aware of Probiotics and their importance.  Probiotics are the usual bacteria that all animals need for their digestive well being but have been largely eliminated along with the pathogenic bacteria thru the use of antibiotics.

Sub therapeutic levels of antibiotics in particular have been used as feed additives for years, to have them act to promote growth. As such, there wasn't any anticipated change at the levels used on pathogens and non pathogens - a "static" state in this regard. Because certain strains of bacteria become resistant to antibiotics, the positive effect (on growth) by using antibiotics is dynamic, not static and as we now know, altered not only the biological activity within the animal, but caused problems in other areas of a dynamic nature never anticipated.

There is also a growing consumer demand to ban antibiotics and other sub therapeutic agents as feed additives because of their connection with residues in food and transferable antibiotic resistance through bacterial resistance factor.
The extensive use of antibiotics and other agents in treating bacterial enteritis is somewhat paradoxical. Although these agents might be successful initially, their benefits are often nullified by post antibiotic diarrhea. Diarrhea can severely compromise an animal's health and prolong its time to market weight.

Diarrhea occurs because antibiotics suppress the normal intestinal bacteria and allow abnormal overgrowth of pathogens, which cause disease. By removing the producers of volatile fatty acids, anti microbial agents also remove an important restraint on the growth of yeast and fungi, making them more invasive." Although the pathogenesis of antibiotic-associated diarrhea is poorly understood, studies evaluating gastrointestinal and fecal composition during antibiotic therapy have demonstrated a decrease or disappearance of L. acidophilus."

Regarding the efficacy of antibiotics as growth promotants, any improvement in growth rate and feed efficiency is inversely related to the performance level of untreated control groups. This suggests that growth promotants work to palliate the depressing effects of unbalanced diets, microbial disease, poor environment, and other stressful conditions, rather than actually promoting growth

The discovery that antibiotics included in the feed of chickens and pigs would improve their growth rate implies the existence of an intestinal microflora that depresses growth. This observation was confined by demonstrating that antibiotics added to the diet of germ-free chicks did not increase their growth rate. A number of trials have been conducted contrasting the effects of feeding probiotics versus antibiotics. Probiotics offer the same benefits in animals as low dose antibiotics when used as growth promotants. In addition, they aid in feed conversion, and in some countries are used as prophylactics against enteritis.

Using preparations of live, naturally occurring microorganisms helps restore and maintain the proper balance of beneficial microflora in the intestinal tract during times of stress, disease, and following antibiotic therapy.

What Proof is there that Probiotics work?
There is a lack of testing and research done in the area of probiotics. Society is becoming more aware that democracy is yet in it's infancy and that much of what is really going on is not necessarily because of its good benefit for the people or the planet. We can thank the hard work of many for their integrity and perseverance to expose the bare truth free from political and religious dogma. There has been little interest in probiotics with literally its enemy antibiotics in the guts of our livestock and our own bodies.
You will notice more interest in the near future. Again, it is not a matter of wanting to be right about a subject or a product. Simply observe and copy nature.
Proof...I have found little research in the area for livestock. There is much more information about human probiotics, which is essentially the same.

Bio-ag has done some of its own research and testing. Most of it is posted on our website. www.bio-ag.com

• Bio-ag Swine Test#1

• Utah State University Study - Evaluates Effect of Fermentation Aids on Rumen Bacteria

• Broiler Breeder Laying Hens Study

• User Report - EnzoLac Broiler Operation

• Testing of EnzoLac - Poultry Research Study

    All tests and testimonials show that EnzoLac produces better health for livestock, more productivity and in the end is more cost effective, saves on stress for the animal and farmer, less veterinarian bills, and all around is better for the environment and LIFE in general.

Medical Validation of Probiotics Extremely Slow....9. CIIM Abstract: Probiotics: Time for a Dose of Realism http://www.horizonpress.com/ciim/
       CIIM Abstract Curr. Issues Intestinal. Microbiol. (2003) 4: 33-42 Probiotics: Time for a Dose of Realism Gerald W. Tannock Department of Microbiology, University of Otago, Dunedin, New Zealand There is already a long research and retail history of probiotics, but progress in the scientific and medical validation of these products has been extremely slow. Even now, adequate information by which the consumer and health professional can judge the efficacy and safety of retailed probiotics is lacking.

Applications:

Early Life: The importance of early administration to the young animal of EnzoLac as a competitive exclusion agent is critical to successful development of beneficial bacteria in the digestive tract, to provide the barrier needed to resist pathogenic bacteria colonization. The earlier the better.
It is not just the quantity of friendly bacteria, it is the integrity of the bacteria itself and their ability to survive in high levels of stomach acids.
EnzoLac was produced to withstand severe stomach acids.

Conclusion:

In a world demanding food safety, the use of EnzoLac becomes a very important tool in the farm manager's program of control. Its use, timing and applications will grow as research and field experiences are run and documented. Already, research has been done with respect to EnzoLac in minimizing salmonella risk and interesting results have been shown in the reduction of E.coli and campylobacter loads. Testimonials from farm operators and managers attest to the efficacy of our probiotic, EnzoLac.

Probiotic Links: Some useful sources for information on probiotics. There is a lack of good solid research on probiotics.

Agriculture : A Vision for the Future - Bio-Ag Enews Letter#2.....10/2002........Probiotics 'What's the Hype' .....(History and the use of Probiotics)

Current Issues in Intestinal Microbiology http://www.horizonpress.com/ciim/

Probiotics - New Zealand  http://www.probiotics.co.nz/prbtcsnz.html

Scientists dedicated to advancing the science of probiotics and prebiotics http://www.isapp.net/

The Probiotics Web Page  http://highveld.com/f/fprobiotic.html

Probiotics: A Critical Review  http://www.horizonpress.com/hsp/books/pro.html

Canadian - Centre for Probiotics  http://www.lhrionhealth.ca/crdcp/index.html

Probiotic Therapy Research Centre  http://www.probiotictherapy.com.au/patients/

Viruses, Bacteria, and Parasites in the Digestive Tract http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/digest/tract.html

Probiotics and dairy products in the United States http://www.usprobiotics.org/

Evaluation of Probiotics for Food  ftp://ftp.fao.org/es/esn/food/wgreport2.pdf

Agriculture : A Vision for the Future - Enews Letter......Recent Articles
A Vision for the Future  - Enews Letter discusses the issues that confront global agricultural methods and technologies today - environmental concerns, food quality, farm/rural life. We research controversial subjects pertinent to the agricultural industry, and inform with the future of our planet in view.

Future Articles:

Overview - Viruses, bacteria and parasites know no boundaries!

Factory Farms: Factories and Family Farms

Grocery Chains and the Farmer and the Forces In-between.

Angry farmers; Why?

Update on GMO's

Is your Farm Cancerous?

Agriculture in Harmony with Nature, 'Up to Basics'

Contaminated Water, Mad Cows, Ecoli and Biotics

What is happening to the world's smaller farmers

Bio-Ag Vision
   We are a company dedicated to enhancing the agricultural industry through working with nature naturally.
Bio-Ag has supplied the North American Agricultural Market since 1982 with products and services of
appropriate sustainable technologies. Our research has assisted thousands of farmers in appreciating the
principles of ecological sound agriculture. Some have adapted themselves towards the fastest growing
industry in North America: organic / safe foods, however...

            95% of our customers are conventional farmers, 5% are organic farmers.

We are suppliers of natural agricultural products for feed, soil, livestock, manure additives, mold inhibitors,
health care, water and we service our customers with healthy solutions for a financially successful farm operation.
We manufacture a line of probiotics which is quickly replacing the use of antibiotics and which there is no
other comparable product on the market.
EnzoLac is a probiotic feed supplement and unique in that it combines both the probiotic (a lactic acid lactobacillus fermentation product) and live plant enzymes on a GMO free (genetically modified organisms) wheat shorts carrier. The enzymes enhance the efficiency of the probiotic and creates a balance in the digestive system to ensure optimum health and productivity.
New Solutions with Intelligent Products,
Patrick Wey
Internet Marketing
Bio-Ag Consultants & Distributors Inc.
www.bio-ag.com/
bio-ag@patrickwey.com
 
 

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